ISSN: 2652-5518By Emily Callander, Lucas Calais-Ferreira, Haylee Fox, Sue Malta, John Hopper Summary Medical advancements and increasing age at first pregnancy have contributed to a worldwide increase in multiple births. However, there is very little information available about the costs associated with having more than one baby at a time, and the potential financial impact […]
Issue 6: Conducting clinical trials in twin populations: working with twins and their families
ISSN: 2652-5518By Lisa Yelland, Paulo Ferreira, Lucas Ferreira, Katrina Scurrah, Monica Rankin, Jane Denton, Merryl Harvey, Katherine J Lee, Evie Kendal, Jeffrey M Craig Main points Summary This article discusses the design and implementation of randomised controlled trials which involve only twins, of which very few have been conducted. We outline specific designs that can […]
Issue 1: Twin research designs and analytic approaches
ISSN: 2652-5518 By Katrina J. Scurrah and John L. Hopper Main points Summary The aim of this article is to summarise different types of research study designs involving twins and the ways in which these can be used to address different specific research questions. We describe the advantages and limitations of the various designs, highlight some issues […]
Issue 5: The importance of zygosity knowledge for twins and science
ISSN: 2652-5518By Jeffrey M Craig, Kate Murphy, Tessa L Cutler, Monica Rankin, Jane Denton, Deborah Schofield, Margaret Otlowski, Mark P Umstad, Susan Carrick Main points Summary Zygosity traditionally refers to the degree of genetic similarity between DNA sequences inherited from each parent. For twins, zygosity refers to the degree of genetic similarity within each pair; monozygotic […]
Issue 4: The importance of twin studies in understanding the early life origins of chronic disease
ISSN: 2652-5518By Jeffery M. Craig Main points Summary We now know that many risks for chronic disease originate in early life. All of us are born with a genetic risk inherited from our parents and an environmental risk from our time spent in the womb. Twin studies show that this environmental risk is split unevenly, […]
Issue 3: School achievement in literacy and numeracy: Insights from research using the twin design
ISSN: 2652-5518By Brian Byrne Main points Summary The aim of this article is to summarise what twin research has taught us about Australians’ school achievement, and to outline the implications for students themselves and their families, for teachers and educational policymakers, and for the broader public as it debates education and its funding. Here I […]
Issue 2: Historical perspectives on twins and twin research
ISSN: 2652-5518By Brian Byrne Main points Summary Twins Research Australia (TRA) has two missions. One is to support and encourage the scientific opportunities afforded by twins and other multiple births to understand the human condition, including the origins and treatment of human diseases and related issues. Its other mission is to support twins themselves and […]