Eligibility: identical twin pairs, younger than 25 years of age, who are differently affected by epilepsy, cerebral palsy, autism or an intellectual impairment.
Neurodevelopmental disorders like epilepsy, intellectual disability, autism and cerebral palsy affect the way your brain develops. Since people often have more than one neurodevelopmental disorder, scientists believe that they sometimes have a common cause. For this study, we are inviting monozygotic (identical) twins who are differently affected by one or more of these disorders to participate. We want to understand the causes of the differences in these twin pairs. We hope that this will help us to predict babies at risk of developing a neurodevelopmental disorder so that doctors can more closely watch these babies develop and design better therapies or treatments for them.
Meet the researchers and learn more about the importance of this study in the video below.
If you agree to participate the researchers will:
We will use this data to identify processes during pregnancy or birth which might have contributed to clinical differences between twins, and provide us with detailed information about the diagnosis, which is important for interpreting genetic data.
You can consent to any or all of these extra clinical information requests. All data obtained through these data linkages is confidential and will be linked only by a code number to our research results. At all times the research results will not identify the individuals or families involved.
Who is eligible?
Monozygotic (identical) twins, currently aged less than 25 years, who are differently affected by one or more neurodevelopmental disorders. Where possible, we will also collect a sample from parents. This is important for determining whether any changes to DNA we identify in your family are inherited.
If you are not yet a Twins Research Australia member you will also need to register online here.