When working with twins discordant for disease, a matched case–control study can be applied.
Twins are matched for:
Cockburn, M., Black, W., McKelvey, W. and Mack, T. (2001). Determinants Of Melanoma In A Case-Control Study Of Twins (United States). Cancer causes & control, 12(7), 615-25.
Hamilton, A. S., & Mack, T.M. (2003). Puberty and genetic susceptibility to breast cancer in a case-control study in twins. The New England Journal of Medicine, 348(23), 2313-22.
Oliveira, V. C., Ferreira, M. L., Refshauge, K.M., Maher, C.G., Griffin, A.R., Hopper, J. L. and Ferreira, P. H. (2015). Risk factors for low back pain: insights from a novel case-control twin study. The Spine Journal, 15(1), 50-7.