Dr Craig leads the Early Life Epigenetics Research Group at the Murdoch Children's Research Institute and Department of Paediatrics, University of Melbourne. He has established a number of longitudinal cohorts including the Peri/Postnatal Epigenetic Twins cohort.

Dr Craig is also an internationally recognised expert on twins and works closely with Twins Research Australia. His work focuses on epigenetic changes associated with early development and the link between environmental factors, development and disease, in particular cardiovascular disease and neurodevelopment. He aims to apply this work to develop epigenetic biomarkers reflecting past environment and predicting future disease risk. He has 82 peer-reviewed publications including Nature Genetics, Molecular Cell, EMBO J, PNAS, J Cell Science & Genome Research.